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Friday, February 24th 2006

Prostate Cancer Virus

UCSF and Cleveland Clinic researchers have found a previously unknown virus in a significant number of men suffering from prostate cancer.

While the genetics of prostate cancer are complex, one of the first genes implicated in the process was RNaseL, which serves as an important antiviral defense mechanism. Given the anti-viral role of this gene, some scientists have speculated that a virus could be involved in a subset of prostate cancer cases.

“While we can’t state that this virus causes prostate cancer, these are remarkable findings because of the association of the virus with the mutation,” said Dr. Robert Silverman, collaborating investigator in the study. “This project was possible only because of the willingness of physicians and scientists in different areas of expertise at the two institutions to work closely together towards a common goal, that of identifying a new infectious agent in prostate cancer.”

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